Postdoctoral Scientist - Melmed Lab - Department of Medicine
Company: Cedars-Sinai
Location: Alhambra
Posted on: May 24, 2023
Job Description:
Are you looking to contribute to groundbreaking research? We
look forward to having you join our team!Cedars-Sinai is an
international leader in biomedical research, we translate
discoveries into successful treatments with global impact.Dr.
Shlomo Melmed, MD is looking for a Postdoctoral Scientist to join a
diverse team!The Melmed Laboratory focuses on elucidating
mechanisms of pituitary tumor development and pathogenesis,
translating the study of anterior pituitary function regulation to
the clinic and establishing new modalities of diagnosis and
treatment for pituitary diseases.Working independently but in close
cooperation and in consultation with the Principal Investigator and
other Research Scientists, the Postdoctoral Scientist will perform
routine and complex laboratory procedures throughout training
period. The incumbent may develop, adapt, and implement new
research techniques and protocols. This position is not responsible
for generating grant funds.Primary Duties and Responsibilities:
- May assist in preparation of grant proposals.
- May participate in publications and presentations as author or
co-author.
- Designs and performs experiments.
- Will keep appropriate experimental records and documentation,
and analyze the results.
- Analyzes, interprets, summarizes, and compiles data.
- Operates and maintains equipment and instruments.
- Will investigate the mechanisms of pituitary
tumorigenesis.Department-Specific Responsibilities:Specific
laboratory procedures conducted:
- Plasmid construction
- DNA/RNA/protein extraction
- SDS-polyacrylamide gel electrophoresis
- Western blotting
- Immunoprecipitation
- Luciferase reporter gene assay
- Site-directed mutagenesis
- Glutathione S-transferase (GST) pull-down experiments
- PCR, RT-PCR, quantitative real-time PCR, ELISA, IgG
purification
- DNA digestion, DNA amplification, ligation and sub-cloning, DNA
or siRNA transfection, and direct sequencing
- Mammalian cell culture and transfection
- Blood and organ collection (from rats and mice)
- Isolation of primary hepatocyte (rat)
- Primary culture of anterior pituitary cells (mice)
- Injection into tail vein of mice
- In vivo knockdown experiment by antisense
oligonucleotide--Education:Doctorate (MD, PhD, VMD, or DDS) in area
directly related to field of research specialization is
required.Experience:
- Acquires technical and theoretical knowledge of research
project and objectives during one to five (1-5) year post-doctoral
appointment.
- Works independently on research projects designed by a mentor
(typically the PI) within area of specialization.
- Demonstrated ability to perform experimental protocols and
procedures, including detailed data collection, and analysis and
operation and maintenance of specialized equipment.Physical
Demands: Able to perform moderate lifting. Able to sit, stand and
walk for prolonged periods of time. Able to read papers and online
documents. Able to operate standard office equipment. Able to
exercise physical ability and perspective acuity to satisfactorily
perform essential job functions.Working Title: Postdoctoral
Scientist - Melmed Lab - Department of MedicineDepartment: Home
Dept - Melmed LabBusiness Entity: Cedars-Sinai Medical CenterJob
Category: Academic/ResearchJob Specialty: PostdoctoralPosition
Type: Full-timeShift Length: 8 hour shiftShift Type: DayBase
Pay:$64,500.00 - $93,600.00
Keywords: Cedars-Sinai, Alhambra , Postdoctoral Scientist - Melmed Lab - Department of Medicine, Healthcare , Alhambra, California
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